SBI-581

CAT: 0931-T61663-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T61663-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Serine Protease
Related Pathways
Others|||Proteases/Proteasome
Bioactivity
SBI-581 is an orally active, potent selective inhibitor of serine-threonine kinase TAO3, with an IC 50 of 42 nM. It effectively promotes the accumulation of TKS5? at RAB11-positive vesicles and inhibits the formation of invadopodia. Additionally, SBI-581 exhibits reasonable pharmacokinetics in mice when administered via IP injection, demonstrating significant antitumor activity [1].
Molecular Formula
C24H21N3O2
Molecular Weight
383.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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