SBI-581
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No


SBI-581
Target :
Others|||Serine ProteaseRelated Pathways :
Others|||Proteases/ProteasomeBioactivity :
SBI-581 is an orally active, potent selective inhibitor of serine-threonine kinase TAO3, with an IC 50 of 42 nM. It effectively promotes the accumulation of TKS5? at RAB11-positive vesicles and inhibits the formation of invadopodia. Additionally, SBI-581 exhibits reasonable pharmacokinetics in mice when administered via IP injection, demonstrating significant antitumor activity [1].Molecular Formula :
C24H21N3O2Molecular Weight :
383.44Shipping Conditions :
Cool packStorage Temperature :
-20°C

