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Anti-inflammatory agent 22

CAT: 0931-T61548-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61548-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2721484-76-8
Target
Others, TNF
Related Pathways
Apoptosis, Others
Bioactivity
Anti-inflammatory agent 22 (compound 14a) is a potent orally active compound with anti-inflammatory properties, effectively inhibiting LPS-induced TNF-α production with an IC50 of 14.6 μM. Additionally, Anti-inflammatory agent 22 prevents adipogenesis and effectively suppresses limb lymphedema volume in mice, holding promise for treating inflammation-related conditions, particularly lymphedematous tissue disorders [1].
Smiles
C(/C=C/C1=CC(O)=C(O)C=C1)(=O)C2=C(OC(=O)C3=CC=CC=C3)C=C(O)C=C2
Molecular Formula
C22H16O6
Molecular Weight
376.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C