EGFR-IN-51

CAT: 0931-T61513-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61513-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2418549-32-1

Target

Others, Apoptosis, EGFR

Related Pathways

Apoptosis, Others, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

Bioactivity

EGFR-IN-51 (Compound 6) is a highly potent EGFR inhibitor with IC50 values of 0.493, 102.60, and 461.63 μM against EGFR, EGFR L858R-TK, and EGFR T790M-TK targets, respectively. Additionally, EGFR-IN-51 exhibits cytotoxicity against cancer cell lines, effectively inducing apoptosis [1].

Smiles

N(C(NC=1C=C2C(=CC1)OCO2)=S)C=3C4=C(N=C5C3C=CC=C5)C=CC=C4

Molecular Formula

C21H15N3O2S

Molecular Weight

373.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
MBS5804217	EGFR-IN-51
sc-80543	EGFR (EGFR.1)
A4495-10	NCH 51
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468386-01	Tyrphostin 51
256487-01	Ro 51
GW3598-5mg	AMG-51
sc-136247	SNX1 (51)
MBS3606979	PKCiota-IN-51
MBS5777994	PBI-51

EGFR-IN-51

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