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AChE/BChE-IN-9

CAT: 0931-T61397-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61397-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2761542-55-4
Target
Others, ROS Kinase, Cholinesterase (ChE)
Related Pathways
Others, Neuroscience, Tyrosine Kinase/Adaptors
Bioactivity
AChE/BChE-IN-9 (Compound 7a) is a potent, orally active inhibitor of AChE and BChE, with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. It also demonstrates effective antioxidant activity (IC50 = 57.35 μM), chelates iron, and modulates amyloid β 1-42 aggregation. Notably, AChE-IN-16 can cross the blood-brain barrier [1].
Smiles
N(C(CNC(/C=C/C1=CC(OC)=C(O)C=C1)=O)=O)C=2C=C3C(=CC2)NC=C3
Molecular Formula
C20H19N3O4
Molecular Weight
365.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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