MRK-623

CAT: 0931-T61176-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T61176-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
461449-78-5
Target
Others|||GABA Receptor
Related Pathways
Neuroscience|||Membrane transporter/Ion channel|||Others
Bioactivity
MRK-623 (Compound 14k) is a potent, orally active agonist of the GABA A receptor with high affinity for subunits ?1, ?2, ?3, and ?5, exhibiting Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM, respectively. Notably, MRK-623 demonstrates anxiolytic effects [1].
Smiles
C(C)(C)(O)C1=NC=2N(C(=CN2)C3=CC(=C(F)C=C3)C=4C=CC=NC4)C=C1
Molecular Formula
C20H17FN4O
Molecular Weight
348.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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