LND 623

• Description:

  LND 623 is an inotropic aminosteroid with positive inotropic properties. LND 623 inhibits Na+/K+ ATPase activity. The LD50 of LND 623 infused i.v. is around 45 mg/kg, a value ten times higher than the LD50 for Ouabain (HY-B1457) [1].

• UNSPSC:

  12352005

• Target:

  Na+/K+ ATPase

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/lnd-623.html

• Smiles:

  O[C@H]([C@@H]([C@H]([C@H](C)O1)O)O)[C@H]1O[C@H]2CC[C@]3(C)[C@@]4([H])CC[C@]5(C)[C@@H]([C@H](O)C)CC[C@]5(N)[C@]4([H])CC[C@]3([H])C2

• Molecular Formula:

  C27H47NO6

• Molecular Weight:

  481.67

• References & Citations:

  [1]Jarreau FX, et al. A new inotropic aminosteroid: LND 623. Eur Heart J. 1984 Dec;5 Suppl F:309-14.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  90520-42-6