B-Raf IN 11

• Target:

  Raf

• Related Pathways:

  MAPK

• Purity:

  0.9995

• Bioactivity:

  B-Raf IN 11 is a novel selective inhibitor. The DFG-in conformation of the B-Raf kinase V600E mutant is superior to the DFG-out conformation in colorectal cancer.

• Smiles:

  C (=O) (C=1C=2C (NC1) =NC=C (Br) C2) C3=C (F) C (NS (CCC) (=O) =O) =CC=C3F

• Molecular Formula:

  C17H14BrF2N3O3S

• Molecular Weight:

  458.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  918504-27-5