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Cibenzoline

CAT: 0931-T60428-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60428-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
53267-01-9
Target
Potassium Channel, Others
Related Pathways
Others, Membrane transporter/Ion channel
Bioactivity
Cibenzoline is an antiarrhythmic agent that inhibits the KATP channel by directly affecting the pore-forming Kir6.2 subunit rather than the SUR1 subunit. Cibenzoline shows little anticholinergic activity. Cibenzoline markedly reduces LVPG which has a close relationship with myocardial contractility decreasing. Cibenzoline has the potential for hypertrophic obstructive cardiomyopathy research[1][2].
Smiles
C1C(C2=NCCN2)C1(c1ccccc1)c1ccccc1
Molecular Formula
C18H18N2
Molecular Weight
262.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C