GNE-6640

• Target:

  DUB

• Related Pathways:

  Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Purity:

  0.9959

• Bioactivity:

  GNE-6640 is a non-covalent inhibitor targeting ubiquitin specific peptidase 7 (USP7), exhibiting IC50 values of 0.75 ?M for full-length USP7, 0.43 ?M for the USP7 catalytic domain, 20.3 ?M for full-length USP43, and 0.23 ?M for Ub-MDM2, respectively.

• Smiles:

  CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2[nH]ncc2c1

• Molecular Formula:

  C20H18N4O

• Molecular Weight:

  330.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2009273-67-8