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GNE-6640

CAT: 931-T5461-01Size: 1 mgDry Ice: NoHazardous: No
1 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2009273-67-8
Target
DUB
Related Pathways
Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Purity
0.9959
Bioactivity
GNE-6640 is a non-covalent inhibitor targeting ubiquitin specific peptidase 7 (USP7), exhibiting IC50 values of 0.75 ?M for full-length USP7, 0.43 ?M for the USP7 catalytic domain, 20.3 ?M for full-length USP43, and 0.23 ?M for Ub-MDM2, respectively.
Smiles
CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2[nH]ncc2c1
Molecular Formula
C20H18N4O
Molecular Weight
330.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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