Products for Research Use Only

JNJ-6640

CAT: 0931-T212088-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T212088-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
JNJ-6640 is an inhibitor targeting Mycobacterium PurF, the first enzyme in the de novo purine biosynthesis pathway, with potent antitubercular activity. It exhibits bactericidal properties against Mycobacterium tuberculosis in vitro, with a MIC90 of 8.6 nM. By disrupting de novo purine biosynthesis, JNJ-6640 inhibits Mycobacterium tuberculosis DNA replication in vivo. Demonstrating antitubercular efficacy in acutely infected mice, JNJ-6640 is applicable for tuberculosis research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C