ARV-771

• Target:

  Epigenetic Reader Domain|||PROTACs

• Related Pathways:

  PROTAC|||Chromatin/Epigenetic

• Purity:

  0.9969

• Bioactivity:

  ARV-771 is an effective BET degrader based on PROTAC technology. The Kd for BRD2 (1), BRD2 (2), BRD3 (1), BRD3 (2), BRD4 (1) and BRD4 (2) are 34 and 4.7 respectively. , 8.3, 7.6, 9.6 and 7.6 nM.

• Smiles:

  CC=1C2=C(N3C([C@H](CC(NCCOCCCOCC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4)C(C)(C)C)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C

• Molecular Formula:

  C49H60ClN9O7S2

• Molecular Weight:

  986.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1949837-12-0