ARV-825

• Target :

  Epigenetic Reader Domain|||PROTACs

• Related Pathways :

  Chromatin/Epigenetic|||PROTAC

• Purity :

  0.98

• Bioactivity :

  ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested.

• Smiles :

  CC=1C2=C(N3C([C@H](CC(NC4=CC=C(OCCOCCOCCOCCNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)C=C4)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C

• Molecular Formula :

  C46H47ClN8O9S

• Molecular Weight :

  923.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1818885-28-7