AG-825

• Target :

  Apoptosis|||EGFR|||Adrenergic Receptor

• Related Pathways :

  Neuroscience|||Apoptosis|||JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||GPCR/G Protein

• Purity :

  0.9952

• Bioactivity :

  AG-825 (Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 ?M.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.AG-825 (Tyrphostin C15) is a potentially active molecule for overcoming manganese-induced neurotoxicity or the development of Alzheimer's disease, and promotes apoptosis in human neutrophils, which could be used in the study of breast cancer.

• Smiles :

  COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2nc3ccccc3s2)c1O

• Molecular Formula :

  C19H15N3O3S2

• Molecular Weight :

  397.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  149092-50-2