AG-825

CAT: 0931-MF-0014884-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0014884-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
149092-50-2
Target
Apoptosis|||EGFR|||Adrenergic Receptor
Related Pathways
Neuroscience|||Apoptosis|||JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||GPCR/G Protein
Purity
0.9952
Bioactivity
AG-825 (Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 ?M.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.AG-825 (Tyrphostin C15) is a potentially active molecule for overcoming manganese-induced neurotoxicity or the development of Alzheimer's disease, and promotes apoptosis in human neutrophils, which could be used in the study of breast cancer.
Smiles
COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2nc3ccccc3s2)c1O
Molecular Formula
C19H15N3O3S2
Molecular Weight
397.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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