GP 1a

CAT: 0931-MF-0097577-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0097577-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
511532-96-0
Target
Cannabinoid Receptor|||PERK
Related Pathways
Apoptosis|||GPCR/G Protein
Purity
0.9996
Bioactivity
GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTP?S and ?-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and increases P-ERK1/2 expression in HL-60 cells in vitro. GP 1a is beneficial for skin wound healing. GP 1a inhibits inflammation and fibrogenesis while promoting epithelial re-formation.
Smiles
C(NN1CCCCC1)(=O)C=2C3=C(N(N2)C4=C(Cl)C=C(Cl)C=C4)C=5C(C3)=CC(C)=CC5
Molecular Formula
C23H22Cl2N4O
Molecular Weight
441.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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