GP 1a

• Target:

  Cannabinoid Receptor|||PERK

• Related Pathways:

  Apoptosis|||GPCR/G Protein

• Purity:

  0.9996

• Bioactivity:

  GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTP?S and ?-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and increases P-ERK1/2 expression in HL-60 cells in vitro. GP 1a is beneficial for skin wound healing. GP 1a inhibits inflammation and fibrogenesis while promoting epithelial re-formation.

• Smiles:

  C(NN1CCCCC1)(=O)C=2C3=C(N(N2)C4=C(Cl)C=C(Cl)C=C4)C=5C(C3)=CC(C)=CC5

• Molecular Formula:

  C23H22Cl2N4O

• Molecular Weight:

  441.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  511532-96-0