GP-82996

CAT: 0931-T21720-01Size: 1 mgDry Ice: NoHazardous: No

CAT#:0931-T21720-01Size:1 mg

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PRICE

AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

1 / 1

CAS Number

359886-84-3

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9994

Bioactivity

GP-82996 (CINK4) is a pharmacological inhibitor specifically targeting CDK4/6, exhibiting IC50 values of 1.5 ?M for CDK4/cyclin D1, 5.6 ?M for CDK6/cyclin D1, and 25 ?M for Cdk5/p35. It effectively induces apoptosis in U2OS cancer cells, positioning it as a potential investigational tool in cancer research [1] [2].

Smiles

C(N1C=2C(=CC(NC=3N=C(N[C@@H]4CC[C@@H](O)CC4)C=C(NCC)N3)=CC2)C=C1)C5=CC=CC=C5

Molecular Formula

C27H32N6O

Molecular Weight

456.58

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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