GP-82996

• Target :

  CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Purity :

  0.9994

• Bioactivity :

  GP-82996 (CINK4) is a pharmacological inhibitor specifically targeting CDK4/6, exhibiting IC50 values of 1.5 ?M for CDK4/cyclin D1, 5.6 ?M for CDK6/cyclin D1, and 25 ?M for Cdk5/p35. It effectively induces apoptosis in U2OS cancer cells, positioning it as a potential investigational tool in cancer research [1] [2].

• Smiles :

  C(N1C=2C(=CC(NC=3N=C(N[C@@H]4CC[C@@H](O)CC4)C=C(NCC)N3)=CC2)C=C1)C5=CC=CC=C5

• Molecular Formula :

  C27H32N6O

• Molecular Weight :

  456.58

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  359886-84-3