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DUTP (trisodium)

CAT: 0804-HY-W017068-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W017068-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DUTP trisodium (2´-Deoxyuridine, 5´-Triphosphate) is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver[1][2][3][4].
CAS Number
102814-08-4
Product Name Alternative
2'-Deoxyuridine-5'-triphosphate (trisodium salt)
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H335, H360
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dutp-trisodium.html
Purity
99.74
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 125 mg/mL (ultrasonic)
Smiles
O=P(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C=C2)=O)=O)O1
Molecular Formula
C9H12N2Na3O14P3
Molecular Weight
534.09
Precautions
H315, H317, H319, H335, H360
References & Citations
[1]Nayun Kim, et al. dUTP incorporation into genomic DNA is linked to transcription in yeast. Nature. 2009 Jun 25;459 (7250) :1150-3.|[2]Grafstrom, R. H., et al., (1978) . The incorporation of uracil into animal cell DNA in vitro. Cell, 15 (1), 131–140.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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