8 (S) -HETE

• Target:

  Others|||PPAR

• Related Pathways:

  Others|||Metabolism|||DNA Damage/DNA Repair

• Bioactivity:

  8 (S) -HETE, a major lipoxygenase product in PMA-treated murine epidermis, activates mouse keratinocyte protein kinase C with an IC50 of 100 ?M and selectively activates PPAR? at concentrations as low as 0.3 ?M. The stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.

• Smiles:

  [C@H](C/C=C\CCCC(O)=O)(/C=C/C=C\C/C=C\CCCCC)O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  98462-03-4