(±) 5-HEPE

(±) 5-HEPE

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  (±) 5-HEPE is produced by non-enzymatic oxidation of EPA and contains equal amounts of 5 (S) -HEPE and 5 (R) -HEPE. The biological activity of (±) 5-HEPE is likely mediated by one of the individual isomers, most commonly the 5 (S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, including 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.

• Smiles:

  CC\C=C/C\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O

• Molecular Formula:

  C20H30O3

• Molecular Weight:

  318.457

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  83952-40-3