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20-HEPE

CAT: 0931-T37092-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0931-T37092-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
116477-57-7
Target
Others, PPAR
Related Pathways
Metabolism, Others, DNA Damage/DNA Repair
Bioactivity
20-HEPE, a metabolite of eicosapentaenoic acid, is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter at a concentration of 10 μM. 20-HEPE also activates murine transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks antinociceptive activity in rats.
Smiles
OCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Molecular Formula
C20H30O3
Molecular Weight
318.457
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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