20-HEPE

• Target:

  Others|||PPAR

• Related Pathways:

  Metabolism|||Others|||DNA Damage/DNA Repair

• Bioactivity:

  20-HEPE, a metabolite of eicosapentaenoic acid, is formed via ?-oxidation of EPA by cytochrome P450 (CYP) ?-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor ? (PPAR?) in COS-7 cells expressing a luciferase reporter at a concentration of 10 ?M. 20-HEPE also activates murine transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks antinociceptive activity in rats.

• Smiles:

  OCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

• Molecular Formula:

  C20H30O3

• Molecular Weight:

  318.457

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  116477-57-7