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CAY10486

CAT: 0931-T36549-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36549-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
615264-52-3
Target
Others, Acyltransferase
Related Pathways
Metabolism, Others
Bioactivity
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
Smiles
[C@@H](CC1=CC=CC=C1)(NC(C=CC2=CC=C(O)C=C2)=O)C(OC)=O
Molecular Formula
C19H19NO4
Molecular Weight
325.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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MBS5802531CAY10486

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