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CAY10485

CAT: 0931-T35984-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T35984-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
615264-62-5
Target
Others|||Acyltransferase
Related Pathways
Metabolism|||Others
Bioactivity
Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 values of 95 and 81 ?M, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins by 91% at a concentration of 2 ?M.
Smiles
[C@H](C(OCC1=CC=CC=C1)=O)(NC(CCC2=CC(O)=C(O)C=C2)=O)CC(OCC3=CC=CC=C3)=O
Molecular Formula
C27H27NO7
Molecular Weight
477.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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