QO-58

CAT: 0931-T28483Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T28483Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1259536-62-3
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9917
Bioactivity
QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, dose-dependently activating Kv7 currents, enhancing native neuronal M currents, and causing a decrease in evoked action potentials. It has anti-nociceptive effects on inflammatory pain and can be used for neuronal excitability disorders.
Smiles
O=C1C=C(NC2=C(C=3C=CC=CC3)C(=NN12)C(F)(F)F)C=4C=C(F)C(Cl)=NC4Cl
Molecular Formula
C18H8Cl2F4N4O
Molecular Weight
443.18
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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