QO-58

• Target:

  Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Purity:

  0.9917

• Bioactivity:

  QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, dose-dependently activating Kv7 currents, enhancing native neuronal M currents, and causing a decrease in evoked action potentials. It has anti-nociceptive effects on inflammatory pain and can be used for neuronal excitability disorders.

• Smiles:

  O=C1C=C(NC2=C(C=3C=CC=CC3)C(=NN12)C(F)(F)F)C=4C=C(F)C(Cl)=NC4Cl

• Molecular Formula:

  C18H8Cl2F4N4O

• Molecular Weight:

  443.18

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1259536-62-3