LEI-101

• Target:

  Others|||Cannabinoid Receptor

• Related Pathways:

  GPCR/G Protein|||Others

• Bioactivity:

  LEI-101 is a potent, selective, and orally bioavailable cannabinoid CB2 receptor agonist, with a pEC50 of 8 for hCB2, and a pKi of less than 4 for hERG. LEI-101 is approximately 100-fold more potent in binding to CB2 receptors than to CB1 receptors. It has therapeutic potential in diseases associated with inflammation and/or oxidative stress, including kidney disease [1] [2].

• Smiles:

  O=C1N(C(=O)CN1CC2=CC=C(C=C2)C=3N=C(CN4CCS(=O)(=O)CC4)C(F)=CC3)C5CC5

• Molecular Formula:

  C23H25FN4O4S

• Molecular Weight:

  472.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1228660-00-1