LEI-800

• Target:

  DNA/RNA Synthesis|||Antibacterial

• Related Pathways:

  Cell Cycle/Checkpoint|||Microbiology/Virology|||DNA Damage/DNA Repair

• Bioactivity:

  LEI-800, a DNA gyrase inhibitor, exhibits its potency with an IC50 value of 35 nM. This compound has significant antibacterial activity, demonstrated by MIC values of 3.1 ?M and 6.25 ?M against Escherichia coli and Klebsiella pneumoniae, respectively.

• Smiles:

  S(NC[C@H]1N[C@H](CC1)C2=CC=C(C=C2)C=3C=CC=NC3)(=O)(=O)C=4C5=C(C=CC4)C=NC=C5

• Molecular Formula:

  C25H24N4O2S

• Molecular Weight:

  444.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3040218-10-5