LEI-800

CAT: 0931-T88679-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T88679-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3040218-10-5
Target
DNA/RNA Synthesis|||Antibacterial
Related Pathways
Cell Cycle/Checkpoint|||Microbiology/Virology|||DNA Damage/DNA Repair
Bioactivity
LEI-800, a DNA gyrase inhibitor, exhibits its potency with an IC50 value of 35 nM. This compound has significant antibacterial activity, demonstrated by MIC values of 3.1 ?M and 6.25 ?M against Escherichia coli and Klebsiella pneumoniae, respectively.
Smiles
S(NC[C@H]1N[C@H](CC1)C2=CC=C(C=C2)C=3C=CC=NC3)(=O)(=O)C=4C5=C(C=CC4)C=NC=C5
Molecular Formula
C25H24N4O2S
Molecular Weight
444.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C