HBF-0259

CAT: 0931-MF-0015485-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0015485-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
957011-15-3
Target
HBV|||Antiviral
Related Pathways
Immunology/Inflammation|||Microbiology/Virology
Purity
0.9988
Bioactivity
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 ?M and a CC50 value of >50 ?M in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.
Smiles
Fc1cccc(Cl)c1C1CC(N=C2N=NNN12)c1ccc(Cl)cc1
Molecular Formula
C16H12Cl2FN5
Molecular Weight
364.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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