HBF-0259

• Target:

  HBV|||Antiviral

• Related Pathways:

  Immunology/Inflammation|||Microbiology/Virology

• Purity:

  0.9988

• Bioactivity:

  HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 ?M and a CC50 value of >50 ?M in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.

• Smiles:

  Fc1cccc(Cl)c1C1CC(N=C2N=NNN12)c1ccc(Cl)cc1

• Molecular Formula:

  C16H12Cl2FN5

• Molecular Weight:

  364.2

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  957011-15-3