HBF-0079

• Description :

  HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma[1].

• UNSPSC :

  12352005

• Target :

  Akt; Apoptosis; mTOR

• Related Pathways :

  Apoptosis; PI3K/Akt/mTOR

• Field of Research :

  Cancer

• Smiles :

  C1(C2=CSC(NC3=NC=CC=N3)=N2)=NC=CC=C1

• Molecular Formula :

  C12H9N5S

• Molecular Weight :

  255.30

• References & Citations :

  [1]Cuconati A, et al. Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells. PLoS One. 2013;8 (1) :e54595.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [315702-93-3]