HBF-0079

• Description:

  HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma[1].

• UNSPSC:

  12352005

• Target:

  Akt; Apoptosis; mTOR

• Related Pathways:

  Apoptosis; PI3K/Akt/mTOR

• Field of Research:

  Cancer

• Smiles:

  C1 (C2=CSC (NC3=NC=CC=N3) =N2) =NC=CC=C1

• Molecular Formula:

  C12H9N5S

• Molecular Weight:

  255.30

• References & Citations:

  [1]Cuconati A, et al. Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells. PLoS One. 2013;8 (1) :e54595.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  315702-93-3