HbF inducer 2

• Target:

  Molecular Glues

• Related Pathways:

  PROTAC

• Purity:

  0.999

• Bioactivity:

  HbF inducer 2 (Compound dWIZ-2) is an orally bioavailable PROTAC molecular glue that degrades the WIZ transcription factor (DC50 = 13 nM) and induces foetal haemoglobin (HbF) expression (EC50 = 100 nM) .

• Smiles:

  O=C1N(CC=2C1=CC=C(OC[C@@H]3N(CC)CCCC3)C2)C4C(=O)NC(=O)CC4

• Molecular Formula:

  C21H27N3O4

• Molecular Weight:

  385.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2654011-51-3