SCH-336

CAT: 0931-T24771-02Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No

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CAT#:0931-T24771-02Size:1 mL - 10 mM (in DMSO)

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

447459-51-0

Target

Cannabinoid Receptor

Related Pathways

GPCR/G Protein

Purity

0.97

Bioactivity

SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100 times more selective to CB2 receptor than CB1. SCH-336 reduced the binding of guanosine 5' -3-o - (sulfur) triphosphate to the membrane containing hCB, inhibited BaF3/CB2 cell migration, inhibited leukocyte migration in mouse delayed hypersensitivity models, and inhibited antigen-induced pulmonary eosinophilia in mouse allergy models.

Smiles

S(=O)(=O)(C1=C(S(=O)(=O)C2=CC=C(OC)C=C2)C=C(OC)C=C1)C3=CC=C([C@@H](NS(C)(=O)=O)C)C=C3

Molecular Formula

C23H25NO8S3

Molecular Weight

539.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide

CAS Number	447459-51-0
PubChem CID	10324989
IUPAC Name	N-[(1S)-1-[4-[4-methoxy-2-(4-methoxyphenyl)sulfonylphenyl]sulfonylphenyl]ethyl]methanesulfonamide
Molecular Formula	C23H25NO8S3
Molecular Weight	539.6
XLogP	2.8
Topological Polar Surface Area	158
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	9
Heavy Atom Count	35
Formal Charge	0
Complexity	994

SMILES

C[C@@H](C1=CC=C(C=C1)S(=O)(=O)C2=C(C=C(C=C2)OC)S(=O)(=O)C3=CC=C(C=C3)OC)NS(=O)(=O)C

InChI

InChI=1S/C23H25NO8S3/c1-16(24-33(4,25)26)17-5-10-20(11-6-17)34(27,28)22-14-9-19(32-3)15-23(22)35(29,30)21-12-7-18(31-2)8-13-21/h5-16,24H,1-4H3/t16-/m0/s1

InChIKey

NXODIUKWAVUFGF-INIZCTEOSA-N

Chemical Structure

2D Structure

CAS: 447459-51-0

CID: 10324989

Formula: C23H25NO8S3

MW: 539.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	539.6
XLogP3	2.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	9
Exact Mass	539.07423028
Monoisotopic Mass	539.07423028
Topological Polar Surface Area	158 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	994
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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T68238-01	MY 336-a
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T28715-01	Sch 34826
T28720-01	Sch 44643
T6979-01	SCH 58261
T19686-01	SCH-37370
T28721-01	Sch 47896

Alternative Products

Catalog	Name
BUP10592-01	SCH-336
XSA45951-01	SCH 336
5815/50	SCH 336 50 mg
5815/10	SCH 336 10 mg
ARC0805	SCH
HY-124373-01	ND-336
441137-01	Aliquat 336
MBS5821533	CHK-336
sc-56864	RARβ (336)
BUP07259-01	ML-336

SCH-336

Chemical Information

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