SCH-37370

CAT: 0931-T19686-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T19686-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
117796-52-8
Target
Histamine Receptor|||PAFR|||Platelet aggregation
Related Pathways
Others|||GPCR/G Protein|||Neuroscience|||Immunology/Inflammation
Purity
0.9992
Bioactivity
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM) .
Smiles
ClC=1C=C2C(C(C=3C(CC2)=CC=CN3)=C4CCN(C(C)=O)CC4)=CC1
Molecular Formula
C21H21ClN2O
Molecular Weight
352.86
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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