SCH-37370

• Target :

  Histamine Receptor|||PAFR|||Platelet aggregation

• Related Pathways :

  Others|||GPCR/G Protein|||Neuroscience|||Immunology/Inflammation

• Purity :

  0.9992

• Bioactivity :

  SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM) .

• Smiles :

  ClC=1C=C2C(C(C=3C(CC2)=CC=CN3)=C4CCN(C(C)=O)CC4)=CC1

• Molecular Formula :

  C21H21ClN2O

• Molecular Weight :

  352.86

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  117796-52-8