SCH-336

• Target:

  Cannabinoid Receptor

• Related Pathways:

  GPCR/G Protein

• Purity:

  0.97

• Bioactivity:

  SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100 times more selective to CB2 receptor than CB1. SCH-336 reduced the binding of guanosine 5' -3-o - (sulfur) triphosphate to the membrane containing hCB, inhibited BaF3/CB2 cell migration, inhibited leukocyte migration in mouse delayed hypersensitivity models, and inhibited antigen-induced pulmonary eosinophilia in mouse allergy models.

• Smiles:

  S(=O)(=O)(C1=C(S(=O)(=O)C2=CC=C(OC)C=C2)C=C(OC)C=C1)C3=CC=C([C@@H](NS(C)(=O)=O)C)C=C3

• Molecular Formula:

  C23H25NO8S3

• Molecular Weight:

  539.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  447459-51-0