APC-6860

• Target:

  Others|||Serine Protease

• Related Pathways:

  Proteases/Proteasome|||Others

• Bioactivity:

  APC-6860 is a trypsin-like serine protease inhibitor with \ (k_i \) values of 0.21, 0.44, 1.5, 16.8, 20, and 30 ?M for uPA, trypsin, tryptase, tPA, thrombin, and factor Xa, respectively. It exhibits a selectivity ratio for tPA versus uPA of 80 and has \ (k_i \) values of 0.1 and 0.082 ?M for human and murine urokinases, respectively. APC-6860 can be utilized for cancer research.

• Smiles:

  NC (=N) c1cc2c (I) cccc2s1

• Molecular Formula:

  C9H7IN2S

• Molecular Weight:

  302.13

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  154628-42-9