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MK-212

CAT: 0931-T21466-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T21466-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
64022-27-1
Target
5-HT Receptor, Others
Related Pathways
Others, GPCR/G Protein, Neuroscience
Bioactivity
MK-212 is a 5HT2C-receptor agonist. Intraperitoneal injection of MK-212 in 0.5 and 1.0 mg/kg increased the blood level of corticosterone in mice and reduced their motor activity. In 0.1 and 0.2 mg/kg, the agonist reduced anxiety with no effect on motor activity.
Smiles
CCC(N)C(O)=O
Molecular Formula
C8H11ClN4
Molecular Weight
198.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

2-Chloro-6-(1-piperazinyl)pyrazine

2-chloro-6-(1-piperazinyl)pyrazine is a N-arylpiperazine.

CAS Number64022-27-1
PubChem CID107992
IUPAC Name2-chloro-6-piperazin-1-ylpyrazine
Molecular FormulaC8H11ClN4
Molecular Weight198.65
XLogP0.5
Topological Polar Surface Area41.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count13
Formal Charge0
Complexity160
SMILES
C1CN(CCN1)C2=CN=CC(=N2)Cl
InChI
InChI=1S/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2
InChIKey
CJAWPFJGFFNXQI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-Chloro-6-(1-piperazinyl)pyrazine
CAS: 64022-27-1
CID: 107992
Formula: C8H11ClN4
MW: 198.65
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight198.65
XLogP30.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass198.0672241
Monoisotopic Mass198.0672241
Topological Polar Surface Area41.1 Ų
Heavy Atom Count13
Formal Charge0
Complexity160
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes