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CL2A

CAT: 0931-T17732-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T17732-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1846605-04-6
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuzumab govitecan utilizes this linker for its drug conjugation[1].
Smiles
C(C1CCC(C(NCC2=CN(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@H](C(NC3=CC=C(COC(O)=O)C=C3)=O)CCCCN)=O)=O)N=N2)=O)CC1)N4C(=O)C=CC4=O
Molecular Formula
C51H79N9O18
Molecular Weight
1106.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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