CL2A-FL118

CAT: 0804-HY-170868Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-170868Size:1 Each
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Description
CL2A-FL118 is a drug-linker for synthesis of ADC molecule Sac-CL2A-FL118[1].
CAS Number
[3025194-00-4]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(OCC1=CC=C(NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN2N=NC(CNC(C3CCC(CN4C(C=CC4=O)=O)CC3)=O)=C2)=O)=O)=O)C=C1)O[C@](C5=C(CO6)C(N7CC8=CC9=CC%10=C(OCO%10)C=C9N=C8C7=C5)=O)(CC)C6=O
Molecular Formula
C72H93N11O23
Molecular Weight
1480.57
References & Citations
[1]Mathi GR, et al. Design, synthesis and biological evaluation of camptothecin analogue FL118 as a payload for antibody-drug conjugates in targeted cancer therapy. Bioorg Med Chem Lett. 2025 Apr 1;118:130085.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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