ML-9

CAT: 0931-T16104-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T16104-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

105637-50-1

Target

Akt, Myosin, Calcium Channel

Related Pathways

Membrane transporter/Ion channel, Cytoskeletal Signaling, Metabolism, PI3K/Akt/mTOR signaling

Purity

0.9969

Bioactivity

ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 causes autophagy by stimulating autophagosome formation and inhibiting their degradation.

Smiles

Cl.Clc1cccc2c(cccc12)S(=O)(=O)N1CCCNCC1

Molecular Formula

C15H18Cl2N2O2S

Molecular Weight

361.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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