Ribociclib succinate

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  0.999

• Bioactivity:

  Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and exhibits over 1,000-fold reduced potency against the cyclin B/CDK1 complex.

• Smiles:

  OC (=O) CCC (O) =O.CN (C) C (=O) c1cc2cnc (Nc3ccc (cn3) N3CCNCC3) nc2n1C1CCCC1

• Molecular Formula:

  C27H36N8O5

• Molecular Weight:

  552.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1374639-75-4