E7090 succinate

CAT: 0931-T72749-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T72749-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1879965-80-6
Target
FGFR|||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Others
Bioactivity
E7090 succinate is a selective, potent, orally-administered inhibitor of FGFR1, FGFR2, and FGFR3 tyrosine kinase activities, demonstrating IC50 values of 0.71 nM (FGFR1), 0.50 nM (FGFR2), 1.2 nM (FGFR3), and 120 nM (FGFR4) .
Smiles
O=C(CCC(O)=O)O.O=C(C1=CC=C(C2CCN(CC2)CCO)C=C1)NC3=NC=CC(OC4=CC5=C(C=C4OCCOC)N(C(NC)=O)C=C5)=C3.O=C(CCC(O)=O)O.O=C(C6=CC=C(C7CCN(CC7)CCO)C=C6)NC8=NC=CC(OC9=CC%10=C(C=C9OCCOC)N(C(NC)=O)C=C%10)=C8.O=C(CCC(O)=O)O
Molecular Formula
C76H92N10O24
Molecular Weight
1529.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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