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Lanraplenib succinate

CAT: 0931-T11824Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T11824Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1800047-00-0
Target
Syk
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.
Smiles
OC(=O)CCC(O)=O.OC(=O)CCC(O)=O.OC(=O)CCC(O)=O.Nc1cncc(n1)-c1cn2ccnc2c(Nc2ccc(cc2)N2CCN(CC2)C2COC2)n1.Nc1cncc(n1)-c1cn2ccnc2c(Nc2ccc(cc2)N2CCN(CC2)C2COC2)n1
Molecular Formula
C58H68N18O14
Molecular Weight
1241.294
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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