Ribociclib hydrochloride

• Target :

  Cell Cycle Arrest|||CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Purity :

  0.9987

• Bioactivity :

  Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that blocks cell cycle progression and inhibits tumor cell proliferation.

• Smiles :

  Cl.O=C(C1=CC=2C=NC(=NC2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5)N(C)C

• Molecular Formula :

  C23H31ClN8O

• Molecular Weight :

  471

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1211443-80-9