GNE-5729

CAT: 0931-MF-0032937-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0032937-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2026635-66-3
Target
IGluR|||NMDAR
Related Pathways
Membrane transporter/Ion channel|||Neuroscience
Purity
0.9985
Bioactivity
GNE-5729 is a positive allosteric modulator of NMDAR with the advantage of crossing the blood-brain barrier and being orally available, with EC50 values of 37 nM, 4.7 ?M and 9.5 ?M for GluN2A, GluN2C and GluN2D, respectively, and can be used for the study of neurological and psychiatric disorders.
Smiles
ClC1=C(N2C(=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)C=C1)[C@H]4[C@H](C#N)C4
Molecular Formula
C17H10Cl2F3N5O
Molecular Weight
428.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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