GNE-0723

• Target :

  IGluR|||NMDAR

• Related Pathways :

  Neuroscience|||Membrane transporter/Ion channel

• Purity :

  0.9991

• Bioactivity :

  GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, with an EC50 of 21 nM for GluN2A. It can cross the blood-brain barrier (BBB) and improve outcomes in Dravet syndrome (DS) and Alzheimer's disease (AD) .

• Smiles :

  C(F)(F)(F)C1=C(N2C(S1)=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)[C@H]4[C@H](C#N)C4

• Molecular Formula :

  C16H8ClF6N5OS

• Molecular Weight :

  467.78

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1883518-31-7