GNE-0723

• Target:

  IGluR|||NMDAR

• Related Pathways:

  Neuroscience|||Membrane transporter/Ion channel

• Purity:

  0.9991

• Bioactivity:

  GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, with an EC50 of 21 nM for GluN2A. It can cross the blood-brain barrier (BBB) and improve outcomes in Dravet syndrome (DS) and Alzheimer's disease (AD) .

• Smiles:

  C (F) (F) (F) C1=C (N2C (S1) =NC (CN3N=C (C (F) (F) F) C=C3Cl) =CC2=O) [C@H]4[C@H] (C#N) C4

• Molecular Formula:

  C16H8ClF6N5OS

• Molecular Weight:

  467.78

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1883518-31-7