GNE-781

• Target:

  Epigenetic Reader Domain|||Histone Acetyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9992

• Bioactivity:

  GNE-781 is a highly potent and selective inhibitor of CBP (IC50: 0.94 nM in TR-FRET assay) . GNE-781 also inhibits BRET and BRD4 (1) (IC50s: 6.2 nM and 5100 nM, respectively) .

• Smiles:

  CNC(=O)N1CCc2c(C1)c(nn2C1CCOCC1)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F

• Molecular Formula:

  C27H33F2N7O2

• Molecular Weight:

  525.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1936422-33-1