GNE-272

• Target:

  Epigenetic Reader Domain|||Histone Acetyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 ?M for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.

• Smiles:

  CC(=O)N1CCc2c(C1)c(Nc1ccc(cc1F)-c1cnn(C)c1)nn2[C@H]1CCOC1

• Molecular Formula:

  C22H25FN6O2

• Molecular Weight:

  424.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1936428-93-1