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Anticancer agent 272

CAT: 931-T207466-01Size: 10 mgDry Ice: NoHazardous: No
10 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Reactive Oxygen Species|||Apoptosis|||Ferroptosis
Related Pathways
Apoptosis|||Immunology/Inflammation|||NF-?B|||Metabolism
Bioactivity
Anticanceragent 272 (Compound 2) is an anticancer agent demonstrating significant activity against bladder cancer cells (T-24) with an IC50 of 2.81 ?M. It depletes glutathione (GSH) through a Fenton-like reaction, generating reactive oxygen species (ROS) and hydroxyl radicals (•OH), thereby inducing apoptosis and ferroptosis. Anticanceragent 272 enhances chemodynamic therapy (CDT) and promotes tumor cell death through mitochondrial dysfunction and autophagy. It holds potential for further research in bladder cancer.
Molecular Formula
C26H34Br2Cl4Cu2N8
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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