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GNE-0946

CAT: 0931-T15398Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15398Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1677667-24-1
Target
ROR
Related Pathways
Metabolism
Bioactivity
GNE-0946 is an effective and selective RORγ/RORc/NR1F3 antagonist (inverse agonist) with an EC50 of 4 nM in HEK-293 cells. It inhibits IL-17 production in human PBMC cells (IC50 = 17 nM) and can be used in autoimmune disease research.
Smiles
O=C(O)C=1C=CC(=CC1O)C=2N=C(C(=O)C=3C(Cl)=CC=CC3C(F)(F)F)N4C=CC=CC24
Molecular Formula
C22H12ClF3N2O4
Molecular Weight
460.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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BUP23167GNE-0946
A20782-50GNE-0946 50mg
A20782-25GNE-0946 25mg
A20782-10GNE-0946 10mg
A20782-5GNE-0946 5mg
A20782-1GNE-0946 1mg
A20782-100GNE-0946 100mg
166522SGC-0946
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