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EHT 1610

CAT: 0931-T15204-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15204-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1425945-60-3
Target
DYRK, GSK-3, NF-κB, Tyrosinase, CDK
Related Pathways
Tyrosine Kinase/Adaptors, NF-κB, Proteases/Proteasome, PI3K/Akt/mTOR signaling, Stem Cells, Cell Cycle/Checkpoint
Purity
0.9859
Bioactivity
EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, regulating cell cycle and inducing cell apoptosis.
Smiles
COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)cc4F)c3c2s1
Molecular Formula
C18H14FN5O2S
Molecular Weight
383.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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