EHT 1610

• Target :

  DYRK|||GSK-3|||NF-?B|||Tyrosinase|||CDK

• Related Pathways :

  Tyrosine Kinase/Adaptors|||NF-?B|||Proteases/Proteasome|||PI3K/Akt/mTOR signaling|||Stem Cells|||Cell Cycle/Checkpoint

• Purity :

  0.9859

• Bioactivity :

  EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively. EHT 1610 has an inhibitory effect on leukemia, regulating cell cycle and inducing cell apoptosis.

• Smiles :

  COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)cc4F)c3c2s1

• Molecular Formula :

  C18H14FN5O2S

• Molecular Weight :

  383.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1425945-60-3