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EHT 5372

CAT: 0931-T61985-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61985-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1425945-63-6
Target
Others, GSK-3, DYRK, CDK
Related Pathways
Others, Stem Cells, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling
Bioactivity
EHT 5372 is a potent and selective inhibitor of DYRK's family kinases. EHT 5372 shows IC 50 s of 0.22, 0.28, 10.8, 93.2, 22.8, 88.8, 59.0, 7.44, 221 nM for DYRK1A, DYRK1B, DYRK2, DYRK3, CLK1, CLK2, CLK4, GSK-3α, GSK-3β.
Smiles
N(C1=C2C3=C(N=C(C(OC)=N)S3)C=CC2=NC=N1)C4=C(Cl)C=C(Cl)C=C4
Molecular Formula
C17H11Cl2N5OS
Molecular Weight
404.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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