CH-0793076

• Target:

  Topoisomerase

• Related Pathways:

  DNA Damage/DNA Repair

• Bioactivity:

  CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein) . CH-0793076 inhibits DNA topoisomerase I (IC50: 2.3 ?M) .

• Smiles:

  C(CCCC)N1C=2C=3C(N=C4C2CN5C4=CC6=C(C5=O)COC(=O)[C@@]6(CC)O)=CC=CC3N=C1

• Molecular Formula:

  C26H26N4O4

• Molecular Weight:

  458.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  534605-78-2