CH 275

• Target:

  Somatostatin

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 ?M, > 10 ?M and > 10?M for human sst1, sst3, sst4, sst2 and sst5 respectively) . Attenuates somatostatin release in the rat nucleus accumbens.

• Smiles:

  C (C=1C=2C (NC1) =CC=CC2) [C@@H]3C (=O) N[C@@H] (CC4=CC=C (CNC (C) C) C=C4) C (=O) N[C@@] ([C@@H] (C) O) (C (=O) N[C@@H] (CC5=CC=CC=C5) C (=O) N[C@@] ([C@@H] (C) O) (C (=O) N[C@@H] (CO) C (=O) N[C@H] (C (O) =O) CSSC[C@H] (N) C (=O) N[C@@H] (CCCCN) C (=O) N[C@@H] (CC6=CC=CC=C6) C (=O) N[C@@H] (CC7=CC=CC=C7) C (=O) N3) [H]) [H]

• Molecular Formula:

  C74H96N14O15S2

• Molecular Weight:

  1485.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  174688-78-9