CDKI-73

• Target :

  Apoptosis|||CDK

• Related Pathways :

  Cell Cycle/Checkpoint|||Apoptosis

• Purity :

  0.9811

• Bioactivity :

  CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM) . It shows selective toxicity to CLL cells (LD50=80 nM) versus normal B cell and normal CD34+ cell (LD50>20 uM) .The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.

• Smiles :

  CNc1nc(C)c(s1)-c1nc(Nc2cccc(c2)S(N)(=O)=O)ncc1F

• Molecular Formula :

  C15H15FN6O2S2

• Molecular Weight :

  394.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1421693-22-2